20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10380 | AS19 | 5-HT Receptor | |
AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM; Ki: 0.6 nM). AS19 is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis: 89.7 nM, 490 nM, 6.6 nM and 98.5 nM, respectively). | |||
T12205 | Ned 19 | Calcium Channel | |
Ned 19 is a selective membrane-permeant non competitive antagonist of NAADP and strongly inhibits tumor growth and vascularization as well as lung metastases in mice. | |||
TP1053L | Protein Kinase C 19-31 acetate | Protein Kinase C 19-31 acetate(121545-65-1 free base),PKC (19-31) acetate | PKC |
Protein Kinase C 19-31 acetate, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is... | |||
T60095 | CCF0058981 | SARS-CoV | |
CCF0058981 (CCF981) is a 3-chlorophenyl analogue, serving as a noncovalent inhibitor of SARS-CoV-2 3CL pro (SC2), demonstrating potent activity with an IC50 of 68 nM. It also exhibits inhibitory effects against SARS-CoV-... | |||
T76781 | Itolizumab | EQ-001 | Others |
Itolizumab (Anti-Human CD6 Recombinant Antibody) is a recombinant anti-CD6 monoclonal antibody that humanizes the extracellular SRCR distal domain 1 of CD6. Itolizumab slows T cell proliferation and inhibits the producti... | |||
T14366 | AZ10606120 dihydrochloride | P2X Receptor | |
AZ10606120 dihydrochloride is a selectable, potent, high-affinity receptor antagonist with K D values of 1.4 and 19 nM at human and rat P2X 7 receptors, respectively. AZ10606120 dihydrochloride inhibits tumor growth and ... | |||
T60165 | VB124 | Monocarboxylate transporter | |
VB124 is an orally active, potent, and selective MCT4 inhibitor, demonstrating specificity in hindering lactate efflux, with IC50 values of 8.6 nM and 19 nM for lactate import and export, respectively, in MDA-MB-231 cell... | |||
TN3651 | Cichoriin | Others | |
Cichoriin is a photosensitive compound, it could be used as herbal photosensitizing agent in treating benign breast tumor in rats. | |||
T9287 | Hydroxychloroquine | 2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol | SARS-CoV , TLR , Parasite , Autophagy |
Hydroxychloroquine (2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol) (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer cells in vitro and inhibiting TLR7/9. It i... | |||
T67747 | CB2R/FAAH modulator-3 | Cannabinoid Receptor , FAAH | |
CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-3 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the ... | |||
T8070 | Nonadecanoic acid | Others | |
Nonadecanoic acid is a long saturated fatty acid found in ox fats and vegetable oils, and in Staphylococcus. It can be used as a phermone by certain insects. | |||
T0134 | Imiquimod | R 837,S-26308 | SARS-CoV , TLR , Autophagy , HSV |
Imiquimod (R 837) is an immune response modifier that acts as a toll-like receptor 7 agonist. | |||
T67745 | CB2R/FAAH modulator-2 | Cannabinoid Receptor , FAAH | |
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, an... | |||
T0194 | Chloroquine phosphate | Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate | SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy |
Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs). | |||
T3921 | Punicalagin | SARS-CoV , HBV | |
Punicalagin is a major ellagitannin found in pomegranates that is reported to produce antioxidant, anti-inflammatory, and anticancer effects. It has been shown to prevent high-fat diet-induced obesity-associated accumula... | |||
T0825 | Ebselen | SPI-1005,PZ-51,CCG-39161 | Phosphatase , Virus Protease , Calcium Channel , COX , HIV Protease |
Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced b... | |||
T39581 | PI3K-IN-19 hydrochloride | PI3K-IN-19 hydrochloride | |
PI3K-IN-19 hydrochloride (WO2017153220, step 5) acts as a phosphatidylinositol-3-kinase (PI3K) inhibitor. | |||
T81083 | STING agonist-19 | ||
STING agonist-19 serves as a precursor for the synthesis of immune-stimulating antibody conjugates (ISACs). | |||
T82166 | HSP90-IN-27 | HSP | |
HSP90-IN-27, also known as compound 19, is an inhibitor of HSP90 [1]. | |||
T81732 | Myosin light chain kinase fragment 11-19 amide | MLCK(11-19) amide | |
Myosin light chain kinase fragment 11-19 amide (MLCK(11-19) amide) serves both as a substrate-specific peptide inhibitor of MLCK and as an inhibitor of hypotonicity-induced Ca2+ entry. This compound has applications in t... |